Repositioning antipsychotic fluphenazine hydrochloride for treating triple negative breast cancer with brain metastases and lung metastases

Triple negative breast cancer (TNBC) patients have a high risk of brain metastases. This deadly disease represents a major challenge for successful treatment, in part because of the poor ability of drugs to penetrate the blood-brain barrier. Antipsychotic drugs show good bioavailability in the brain...

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Dades bibliogràfiques
Publicat a:Am J Cancer Res
Autors principals: Xu, Fuyan, Xia, Yong, Feng, Zhanzhan, Lin, Wentao, Xue, Qiang, Jiang, Jinrui, Yu, Xi, Peng, Cuiting, Luo, Min, Yang, Yufei, Wei, Yuquan, Yu, Luoting
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448056/
https://ncbi.nlm.nih.gov/pubmed/30949404
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