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Down-regulation of Heat Shock Protein HSP90ab1 in Radiation-damaged Lung Cells other than Mast Cells

Ionizing radiation (IR) leads to fibrosing alveolitis (FA) after a lag period of several weeks to months. In a rat model, FA starts at 8 weeks after IR. Before that, at 5.5 weeks after IR, the transcription factors Sp1 (stimulating protein 1) and AP-1 (activator protein 1) are inactivated. To find g...

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Detalhes bibliográficos
Main Authors: Haase, Michael G., Geyer, Peter, Fitze, Guido, Baretton, Gustavo B.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005367/
https://ncbi.nlm.nih.gov/pubmed/24670792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155414529133
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