Cytochrome P450 2C8 ω3-Long-Chain Polyunsaturated Fatty Acid Metabolites Increase Mouse Retinal Pathologic Neovascularization—Brief Report

OBJECTIVE: Regulation of angiogenesis is critical for many diseases. Specifically, pathological retinal neovascularization, a major cause of blindness, is suppressed with dietary ω3-long-chain polyunsaturated fatty acids (ω3LCPUFAs) through antiangiogenic metabolites of cyclooxygenase and lipoxygena...

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Bibliografiske detaljer
Main Authors: Shao, Zhuo, Fu, Zhongjie, Stahl, Andreas, Joyal, Jean-Sébastien, Hatton, Colman, Juan, Aimee, Hurst, Christian, Evans, Lucy, Cui, Zhenghao, Pei, Dorothy, Gong, Yan, Xu, Dan, Tian, Katherine, Bogardus, Hannah, Edin, Matthew L., Lih, Fred, Sapieha, Przemyslaw, Chen, Jing, Panigrahy, Dipak, Hellstrom, Ann, Zeldin, Darryl C., Smith, Lois E.H.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005334/
https://ncbi.nlm.nih.gov/pubmed/24458713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302927
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