Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase

Bacterial enoyl-acyl carrier protein reductase (ENR) catalyzes an essential step in fatty acid biosynthesis. ENR is an attractive target for narrow-spectrum antibacterial drug discovery because of its essential role in metabolism and its sequence conservation across many bacterial species. In additi...

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Detalhes bibliográficos
Main Authors: Ling, Losee L., Xian, Jun, Ali, Syed, Geng, Bolin, Fan, Jun, Mills, Debra M., Arvanites, Anthony C., Orgueira, Hernan, Ashwell, Mark A., Carmel, Gilles, Xiang, Yibin, Moir, Donald T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400533/
https://ncbi.nlm.nih.gov/pubmed/15105103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1541-1547.2004
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