IL-4 receptor alpha single-nucleotide polymorphisms rs1805010 and rs1801275 are associated with increased risk of asthma in a Saudi Arabian population

BACKGROUND: The IL-4 receptor alpha subunit (IL-4Rα), when associated with the common gamma chain receptor, or the IL-13Rα1 subunit, transduces signals to STAT6 in response to IL-4 and IL-13 stimulations. This results in a number of cell-specific responses including Th2 differentiation, lymphocyte p...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Al-Muhsen, Saleh, Vazquez-Tello, Alejandro, Alzaabi, Ashraf, Al-Hajjaj, Mohamed S., Al-Jahdali, Hamdan H., Halwani, Rabih
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2014
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005166/
https://ncbi.nlm.nih.gov/pubmed/24791170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1817-1737.128849
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge