Identification of an immune-regulated phagosomal Rab cascade in macrophages

Interferon-γ (IFN-γ) has been shown to regulate phagosome trafficking and function in macrophages, but the molecular mechanisms involved are poorly understood. Here, we identify Rab20 as part of the machinery by which IFN-γ controls phagosome maturation. We found that IFN-γ stimulates the associatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Pei, Gang, Repnik, Urska, Griffiths, Gareth, Gutierrez, Maximiliano Gabriel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004979/
https://ncbi.nlm.nih.gov/pubmed/24569883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.144923
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