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Identification of an immune-regulated phagosomal Rab cascade in macrophages

Interferon-γ (IFN-γ) has been shown to regulate phagosome trafficking and function in macrophages, but the molecular mechanisms involved are poorly understood. Here, we identify Rab20 as part of the machinery by which IFN-γ controls phagosome maturation. We found that IFN-γ stimulates the associatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pei, Gang, Repnik, Urska, Griffiths, Gareth, Gutierrez, Maximiliano Gabriel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004979/
https://ncbi.nlm.nih.gov/pubmed/24569883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.144923
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