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The p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal release

The p75 neurotrophin receptor (p75, also known as NGFR) is a multifaceted signalling receptor that regulates neuronal physiology, including neurite outgrowth, and survival and death decisions. A key cellular aspect regulating neurotrophin signalling is the intracellular trafficking of their receptor...

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Detalhes bibliográficos
Main Authors: Escudero, Claudia A., Lazo, Oscal M., Galleguillos, Carolina, Parraguez, Jose I., Lopez-Verrilli, Maria A., Cabeza, Carolina, Leon, Luisa, Saeed, Uzma, Retamal, Claudio, Gonzalez, Alfonso, Marzolo, Maria-Paz, Carter, Bruce D., Court, Felipe A., Bronfman, Francisca C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004974/
https://ncbi.nlm.nih.gov/pubmed/24569882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.141754
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