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The Ability of Thyroid Hormone Receptors to Sense T(4) as an Agonist Depends on Receptor Isoform and on Cellular Cofactors
T(4) (3,5,3′,5′-tetraiodo-l-thyronine) is classically viewed as a prohormone that must be converted to the T(3) (3,5,3′-triiodo-l-thyronine) form for biological activity. We first determined that the ability of reporter genes to respond to T(4) and to T(3) differed for the different thyroid hormone...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Endocrine Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004778/ https://ncbi.nlm.nih.gov/pubmed/24673558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1335 |
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