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Autologous albumin enhances the humoral immune response to capsular polysaccharide covalently co-attached to bacteria-sized latex beads

Abundant autologous proteins, like serum albumin, should be immunologically inert. However, individuals with no apparent predisposition to autoimmune disease can develop immune responses to autologous therapeutic proteins. Protein aggregation is a potential major trigger of these responses. Adsorpti...

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Hlavní autoři: Colino, Jesus, Duke, Leah, Snapper, Clifford M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004682/
https://ncbi.nlm.nih.gov/pubmed/24481921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344266
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