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T Cell Epitope Mimicry between Sjögren’s Syndrome Antigen A (SSA)/Ro60 and Oral, Gut, Skin and Vaginal Bacteria.

This study was undertaken to test the hypothesis that Sjogren’s syndrome Antigen A (SSA)/Ro60-reactive T cells are activated by peptides originating from oral and gut bacteria. T cell hybridomas generated from HLA-DR3 transgenic mice recognized 3 regions on Ro60, with core epitopes mapped to amino a...

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Detalhes bibliográficos
Main Authors: Szymula, Agnieszka, Rosenthal, Jacob, Szczerba, Barbara M, Bagavant, Harini, Fu, Shu Man, Deshmukh, Umesh S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004658/
https://ncbi.nlm.nih.gov/pubmed/24576620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.02.004
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