Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages

BACKGROUND: Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans help regulate pathways that control stem cell fate, and therefore represent an excellent tool to manipulate these pathways. Despit...

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Hlavní autoři: Gasimli, Leyla, Hickey, Anne M., Yang, Bo, Li, Guoyun, Rosa, Mitche dela, Nairn, Alison V., Kulik, Michael J., Dordick, Jonathan S., Moremen, Kelley W., Dalton, Stephen, Linhardt, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004645/
https://ncbi.nlm.nih.gov/pubmed/24412195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.01.007
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