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Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages

BACKGROUND: Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans help regulate pathways that control stem cell fate, and therefore represent an excellent tool to manipulate these pathways. Despit...

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Detalhes bibliográficos
Main Authors: Gasimli, Leyla, Hickey, Anne M., Yang, Bo, Li, Guoyun, Rosa, Mitche dela, Nairn, Alison V., Kulik, Michael J., Dordick, Jonathan S., Moremen, Kelley W., Dalton, Stephen, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004645/
https://ncbi.nlm.nih.gov/pubmed/24412195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.01.007
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