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Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages

BACKGROUND: Proteoglycans are found on the cell surface and in the extracellular matrix, and serve as prime sites for interaction with signaling molecules. Proteoglycans help regulate pathways that control stem cell fate, and therefore represent an excellent tool to manipulate these pathways. Despit...

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Détails bibliographiques
Auteurs principaux: Gasimli, Leyla, Hickey, Anne M., Yang, Bo, Li, Guoyun, Rosa, Mitche dela, Nairn, Alison V., Kulik, Michael J., Dordick, Jonathan S., Moremen, Kelley W., Dalton, Stephen, Linhardt, Robert J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004645/
https://ncbi.nlm.nih.gov/pubmed/24412195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.01.007
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