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Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination

Oligodendrocyte precursor cells differentiate to produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. Many aspects of differentiation are regulated by multiple extracellular signals. However, their intracellular signalings remain elusive. We show that Rab35 and...

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Auteurs principaux: Miyamoto, Yuki, Yamamori, Natsuki, Torii, Tomohiro, Tanoue, Akito, Yamauchi, Junji
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004601/
https://ncbi.nlm.nih.gov/pubmed/24600047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0600
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