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BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice

During development of the peripheral nervous system in mammals, Schwann cells wrap their plasma membranes around neuronal axons, forming multiple myelin sheaths. A mature myelin sheath insulates axons and increases nerve conduction velocity while protecting nerve fibers from various stresses such as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Adv
Hauptverfasser: Miyamoto, Yuki, Torii, Tomohiro, Tago, Kenji, Tanoue, Akito, Takashima, Shou, Yamauchi, Junji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938228/
https://ncbi.nlm.nih.gov/pubmed/29740613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aar4471
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