The wing of the enhancer-binding domain of Mu phage transposase is flexible and is essential for efficient transposition.

A tetramer of the Mu transposase (MuA) pairs the recombination sites, cleaves the donor DNA, and joins these ends to a target DNA by strand transfer. Juxtaposition of the recombination sites is accomplished by the assembly of a stable synaptic complex of MuA protein and Mu DNA. This initial critical...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Clubb, R T, Mizuuchi, M, Huth, J R, Omichinski, J G, Savilahti, H, Mizuuchi, K, Clore, G M, Gronenborn, A M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8577730/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.3.1146
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