The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification

There are five members of the RFX family of transcription factors in mammals. While RFX5 plays a well-defined role in the immune system, the functions of RFX1 to RFX4 remain largely unknown. We have generated mice with a deletion of the Rfx3 gene. RFX3-deficient mice exhibit frequent left-right (LR)...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Bonnafe, E., Touka, M., AitLounis, A., Baas, D., Barras, E., Ucla, C., Moreau, A., Flamant, F., Dubruille, R., Couble, P., Collignon, J., Durand, B., Reith, W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2004
Soggetti:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400456/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15121860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.10.4417-4427.2004
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