The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification

There are five members of the RFX family of transcription factors in mammals. While RFX5 plays a well-defined role in the immune system, the functions of RFX1 to RFX4 remain largely unknown. We have generated mice with a deletion of the Rfx3 gene. RFX3-deficient mice exhibit frequent left-right (LR)...

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Detalhes bibliográficos
Main Authors: Bonnafe, E., Touka, M., AitLounis, A., Baas, D., Barras, E., Ucla, C., Moreau, A., Flamant, F., Dubruille, R., Couble, P., Collignon, J., Durand, B., Reith, W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400456/
https://ncbi.nlm.nih.gov/pubmed/15121860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4417-4427.2004
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