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The YXXΦ motif within the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein is crucial for its intracellular transport

BACKGROUND: The SARS coronavirus (SARS-CoV) 3a protein functions as an ion channel, induces apoptosis and is important for viral pathogenesis. It is expressed on the cell surface and contains a tyrosine-based sorting motif and a di-acidic motif, which may be crucial for its intracellular trafficking...

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Bibliographic Details
Main Authors: Minakshi, Rinki, Padhan, Kartika
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004515/
https://ncbi.nlm.nih.gov/pubmed/24762043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-75
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