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Acquisition of Hrs, an Essential Component of Phagosomal Maturation, Is Impaired by Mycobacteria

Pathogenic mycobacteria survive within macrophages by precluding the fusion of phagosomes with late endosomes or lysosomes. Because the molecular determinants of normal phagolysosome formation are poorly understood, the sites targeted by mycobacteria remain unidentified. We found that Hrs, an adapto...

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Detalhes bibliográficos
Main Authors: Vieira, Otilia V., Harrison, Rene E., Scott, Cameron C., Stenmark, Harald, Alexander, David, Liu, Jun, Gruenberg, Jean, Schreiber, Alan D., Grinstein, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC400451/
https://ncbi.nlm.nih.gov/pubmed/15121875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.10.4593-4604.2004
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