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Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP

Nascent phagosomes must undergo a series of fusion and fission reactions to acquire the microbicidal properties required for the innate immune response. Here we demonstrate that this maturation process involves the GTPase Rab7. Rab7 recruitment to phagosomes was found to precede and to be essential...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Harrison, Rene E., Bucci, Cecilia, Vieira, Otilia V., Schroer, Trina A., Grinstein, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12944476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.18.6494-6506.2003
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