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Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP

Nascent phagosomes must undergo a series of fusion and fission reactions to acquire the microbicidal properties required for the innate immune response. Here we demonstrate that this maturation process involves the GTPase Rab7. Rab7 recruitment to phagosomes was found to precede and to be essential...

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Publicat a:Mol Cell Biol
Autors principals: Harrison, Rene E., Bucci, Cecilia, Vieira, Otilia V., Schroer, Trina A., Grinstein, Sergio
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC193691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12944476/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.18.6494-6506.2003
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