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Improved multi-level protein–protein interaction prediction with semantic-based regularization

BACKGROUND: Protein–protein interactions can be seen as a hierarchical process occurring at three related levels: proteins bind by means of specific domains, which in turn form interfaces through patches of residues. Detailed knowledge about which domains and residues are involved in a given interac...

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Detalhes bibliográficos
Main Authors: Saccà, Claudio, Teso, Stefano, Diligenti, Michelangelo, Passerini, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004462/
https://ncbi.nlm.nih.gov/pubmed/24725682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-103
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