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An improved method for scoring protein-protein interactions using semantic similarity within the gene ontology

BACKGROUND: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based on their function using annotation systems like the Gene Ontology (GO). Proteins that interact in the cell are likely to b...

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Main Authors: Jain, Shobhit, Bader, Gary D
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998529/
https://ncbi.nlm.nih.gov/pubmed/21078182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-562
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