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Activation of Liver X Receptor Alleviates Ocular Inflammation in Experimental Autoimmune Uveitis
PURPOSE. To investigate whether a synthetic LXR agonist TO901317 (TO90) ameliorates ocular inflammation in a mouse model of experimental autoimmune uveitis (EAU) and to explore its underlying mechanism. METHODS. EAU was induced with subcutaneous injection of IRBP(161–180) peptide (SGIPYIISYLHPGNTILH...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004425/ https://ncbi.nlm.nih.gov/pubmed/24699378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13323 |
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