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Magnetic Field-Induced T Cell Receptor Clustering by Nanoparticles Enhances T Cell Activation and Stimulates Antitumor Activity

[Image: see text] Iron–dextran nanoparticles functionalized with T cell activating proteins have been used to study T cell receptor (TCR) signaling. However, nanoparticle triggering of membrane receptors is poorly understood and may be sensitive to physiologically regulated changes in TCR clustering...

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Detalhes bibliográficos
Main Authors: Perica, Karlo, Tu, Ang, Richter, Anne, Bieler, Joan Glick, Edidin, Michael, Schneck, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004316/
https://ncbi.nlm.nih.gov/pubmed/24564881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn405520d
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