Susceptibility to collagen-induced arthritis is modulated by TGFβ responsiveness of T cells

The objective of our study was to determine the regulatory effects that endogenous transforming growth factor β (TGFβ) exerts on T cells in the pathogenesis of collagen-induced arthritis (CIA). CIA was induced in transgenic mice expressing a dominant negative TGFβ type II receptor in T cells under t...

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Bibliographic Details
Main Authors: Schramm, Christoph, Kriegsmann, Jörg, Protschka, Martina, Huber, Samuel, Hansen, Torsten, Schmitt, Edgar, Galle, Peter Robert, Blessing, Manfred
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400430/
https://ncbi.nlm.nih.gov/pubmed/15059274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1039
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