A Hybrid Protein–Polymer Nanoworm Potentiates Apoptosis Better than a Monoclonal Antibody

[Image: see text] B-cell lymphomas continue to occur with a high incidence. The chimeric antibody known as Rituximab (Rituxan) has become a vital therapy for these patients. Rituximab induces cell death via binding and clustering of the CD20 receptor by Fcγ expressing effector cells. Because of the...

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Hlavní autoři: Aluri, Suhaas Rayudu, Shi, Pu, Gustafson, Joshua A., Wang, Wan, Lin, Yi-An, Cui, Honggang, Liu, Shuanglong, Conti, Peter S., Li, Zibo, Hu, Peisheng, Epstein, Alan L., MacKay, John Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004287/
https://ncbi.nlm.nih.gov/pubmed/24484356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn403973g
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