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δ-Deuterium Isotope Effects as Probes for Transition-State Structures of Isoprenoid Substrates

[Image: see text] The biosynthetic pathways to isoprenoid compounds involve transfer of the prenyl moiety in allylic diphosphates to electron-rich (nucleophilic) acceptors. The acceptors can be many types of nucleophiles, while the allylic diphosphates only differ in the number of isoprene units and...

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Autors principals: Choi, Seoung-ryoung, Breugst, Martin, Houk, Kendall N., Poulter, C. Dale
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004232/
https://ncbi.nlm.nih.gov/pubmed/24665882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500394u
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