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Biosynthesis of a Thiamin Antivitamin in Clostridium botulinum
[Image: see text] Bacimethrin-derived 2′-methoxythiamin pyrophosphate inhibits microbial growth by disrupting metabolic pathways dependent on thiamin-utilizing enzymes. This study describes the discovery of the bacimethrin biosynthetic gene cluster of Clostridium botulinum A ATCC 19397 and in vitro...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American
Chemical Society
2014
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004229/ https://ncbi.nlm.nih.gov/pubmed/24654570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500281a |
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