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Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition

Inhibitors of p38 mitogen-activated protein kinase (MAPK) diminish inflammatory arthritis in experimental animals. This may be effected by diminishing the production of inflammatory mediators, but this kinase is also part of the IL-1 signal pathway in articular chondrocytes. We determined the effect...

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Autori principali: Studer, Rebecca K, Bergman, Rachel, Stubbs, Tiffany, Decker, Kimberly
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC400413/
https://ncbi.nlm.nih.gov/pubmed/14979938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1022
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