A Mutation in the HLA-B(*)2705-Restricted NP(383-391) Epitope Affects the Human Influenza A Virus-Specific Cytotoxic T-Lymphocyte Response In Vitro

Viruses can exploit a variety of strategies to evade immune surveillance by cytotoxic T lymphocytes (CTL), including the acquisition of mutations in or adjacent to CTL epitopes. Recently, an amino acid substitution (R384G) in an HLA-B(*)2705-restricted CTL epitope in the influenza A virus nucleoprot...

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Détails bibliographiques
Auteurs principaux: Berkhoff, E. G. M., Boon, A. C. M., Nieuwkoop, N. J., Fouchier, R. A. M., Sintnicolaas, K., Osterhaus, A. D. M. E., Rimmelzwaan, G. F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2004
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC400375/
https://ncbi.nlm.nih.gov/pubmed/15113903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5216-5222.2004
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