Antigenic Drift in the Influenza A Virus (H3N2) Nucleoprotein and Escape from Recognition by Cytotoxic T Lymphocytes

Viruses exploit different strategies to escape immune surveillance, including the introduction of mutations in cytotoxic T-lymphocyte (CTL) epitopes. The sequence of these epitopes is critical for their binding to major histocompatibility complex (MHC) class I molecules and recognition by specific C...

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Détails bibliographiques
Auteurs principaux: Voeten, J. T. M., Bestebroer, T. M., Nieuwkoop, N. J., Fouchier, R. A. M., Osterhaus, A. D. M. E., Rimmelzwaan, G. F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC112197/
https://ncbi.nlm.nih.gov/pubmed/10888619
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