Antigenic Drift in the Influenza A Virus (H3N2) Nucleoprotein and Escape from Recognition by Cytotoxic T Lymphocytes

Viruses exploit different strategies to escape immune surveillance, including the introduction of mutations in cytotoxic T-lymphocyte (CTL) epitopes. The sequence of these epitopes is critical for their binding to major histocompatibility complex (MHC) class I molecules and recognition by specific C...

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Pubblicato in:	J Virol
Autori principali:	Voeten, J. T. M., Bestebroer, T. M., Nieuwkoop, N. J., Fouchier, R. A. M., Osterhaus, A. D. M. E., Rimmelzwaan, G. F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10888619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.15.6800-6807.2000
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