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Changes of the Secondary Structure of the 5′ End of the Sindbis Virus Genome Inhibit Virus Growth in Mosquito Cells and Lead to Accumulation of Adaptive Mutations

Both the 5′ end of the Sindbis virus (SIN) genome and its complement in the 3′ end of the minus-strand RNA synthesized during virus replication serve as parts of the promoters recognized by the enzymes that comprise the replication complex (RdRp). In addition to the 5′ untranslated region (UTR), whi...

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Bibliografski detalji
Glavni autori: Fayzulin, Rafik, Frolov, Ilya
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC400360/
https://ncbi.nlm.nih.gov/pubmed/15113874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.4953-4964.2004
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