θ Defensins Protect Cells from Infection by Herpes Simplex Virus by Inhibiting Viral Adhesion and Entry

We tested the ability of 20 synthetic θ defensins to protect cells from infection by type 1 and type 2 herpes simplex viruses (HSV-1 and -2, respectively). The peptides included rhesus θ defensins (RTDs) 1 to 3, originally isolated from rhesus macaque leukocytes, and three peptides (retrocyclins 1 t...

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Bibliographic Details
Main Authors: Yasin, Bushra, Wang, Wei, Pang, Mabel, Cheshenko, Natalia, Hong, Teresa, Waring, Alan J., Herold, Betsy C., Wagar, Elizabeth A., Lehrer, Robert I.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400355/
https://ncbi.nlm.nih.gov/pubmed/15113897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5147-5156.2004
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