PIK3CA Gene Amplification and PI3K p110α Protein Expression in Breast Carcinoma

A family of PI3Ks is the lipid kinases, which enhance intracellular pools of phosphatidyl inositol 3,4,5-tri-phosphate (PIP3) through phosphorylating its precursor. Amplifications and deletions of genes, as well as somatic missense of the PIK3CA gene have been described in many human cancer varietie...

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Bibliographic Details
Main Authors: Firoozinia, Mohammad, Zareian Jahromi, Mohammad, Moghadamtousi, Soheil Zorofchian, Nikzad, Sonia, Abdul Kadir, Habsah
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2014
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003548/
https://ncbi.nlm.nih.gov/pubmed/24782652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.8251
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