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PIK3CA Gene Amplification and PI3K p110α Protein Expression in Breast Carcinoma
A family of PI3Ks is the lipid kinases, which enhance intracellular pools of phosphatidyl inositol 3,4,5-tri-phosphate (PIP3) through phosphorylating its precursor. Amplifications and deletions of genes, as well as somatic missense of the PIK3CA gene have been described in many human cancer varietie...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003548/ https://ncbi.nlm.nih.gov/pubmed/24782652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.8251 |
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