The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach

Annona muricata has been used in folk medicine for the treatment of cancer and tumors. This study evaluated the chemopreventive properties of an ethyl acetate extract of A. muricata leaves (EEAML) on azoxymethane-induced colonic aberrant crypt foci (ACF) in rats. Moreover, the cytotoxic compound of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zorofchian Moghadamtousi, Soheil, Rouhollahi, Elham, Karimian, Hamed, Fadaeinasab, Mehran, Firoozinia, Mohammad, Ameen Abdulla, Mahmood, Abdul Kadir, Habsah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393181/
https://ncbi.nlm.nih.gov/pubmed/25860620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122288
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