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Therapeutic potential of statins and the induction of heme oxygenase-1 in preeclampsia()

Heme oxygenase (Hmox) is an endogenous system that offers protection against placental cytotoxic damage associated with preeclampsia. The Hmox1/carbon monoxide (CO) pathway inhibits soluble Flt-1 (sFlt-1) and soluble Endoglin (sEng). More importantly, statins induce Hmox1 and suppress the release of...

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Autori principali: Ramma, Wenda, Ahmed, Asif
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier/North-Holland Biomedical Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003533/
https://ncbi.nlm.nih.gov/pubmed/24503248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jri.2013.12.120
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