Diagnostic effectiveness of quantitative [(18)F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus

INTRODUCTION: PET imaging of amyloid-β (Aβ) in vivo holds promise for aiding in earlier diagnosis and intervention in Alzheimer’s disease (AD) and mild cognitive impairment. AD-like Aβ pathology is a common comorbidity in patients with idiopathic normal pressure hydrocephalus (iNPH). Fifty patients...

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Detalhes bibliográficos
Main Authors: Leinonen, Ville, Rinne, Juha O, Wong, Dean F, Wolk, David A, Trojanowski, John Q, Sherwin, Paul F, Smith, Adrian, Heurling, Kerstin, Su, Mandy, Grachev, Igor D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003513/
https://ncbi.nlm.nih.gov/pubmed/24755237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-46
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