Estimation of amyloid distribution by [(18)F]flutemetamol PET predicts the neuropathological phase of amyloid β-protein deposition

The deposition of the amyloid β-protein (Aβ) in senile plaques is one of the histopathological hallmarks of Alzheimer’s disease (AD). Aβ-plaques arise first in neocortical areas and, then, expand into further brain regions in a process described by 5 phases. Since it is possible to identify amyloid...

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Bibliographic Details
Published in:Acta Neuropathol
Main Authors: Thal, Dietmar Rudolf, Beach, Thomas G., Zanette, Michelle, Lilja, Johan, Heurling, Kerstin, Chakrabarty, Aruna, Ismail, Azzam, Farrar, Gill, Buckley, Christopher, Smith, Adrian P. L.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2018
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132944/
https://ncbi.nlm.nih.gov/pubmed/30123935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1897-9
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