Enhanced Antibody Responses to an HIV-1 MPER Antigen in Mice Reconstituted with Cultured Lymphocytes

We have shown that the protective HIV-1 antibody, 2F5, avidly reacts with a conserved mammalian self-antigen, kynureninase, and that the development of B cells specific for the 2F5 epitope is constrained by immunological tolerance. These observations suggest that the capacity to mount antibody respo...

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Bibliografiske detaljer
Main Authors: Holl, T. Matt, Yang, Guang, Kuraoka, Masayuki, Verkoczy, Laurent, Alam, S. Munir, Moody, M. Anthony, Haynes, Barton F., Kelsoe, Garnett
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003504/
https://ncbi.nlm.nih.gov/pubmed/24591365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302829
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