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Enhanced Antibody Responses to an HIV-1 MPER Antigen in Mice Reconstituted with Cultured Lymphocytes
We have shown that the protective HIV-1 antibody, 2F5, avidly reacts with a conserved mammalian self-antigen, kynureninase, and that the development of B cells specific for the 2F5 epitope is constrained by immunological tolerance. These observations suggest that the capacity to mount antibody respo...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4003504/ https://ncbi.nlm.nih.gov/pubmed/24591365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302829 |
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