Classical Swine Fever Virus Glycoprotein E(rns) Is an Endoribonuclease with an Unusual Base Specificity

The glycoprotein E(rns) of pestiviruses is a virion-associated and -secreted RNase that is involved in virulence. The requirements at the cleavage site in heteropolymeric RNA substrates were studied for E(rns). Limited digestion of heteropolymeric RNA substrates indicated a cleavage 5′ of uridine re...

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Bibliographic Details
Main Authors: Hausmann, Yvonne, Roman-Sosa, Gleyder, Thiel, Heinz-Jürgen, Rümenapf, Till
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400347/
https://ncbi.nlm.nih.gov/pubmed/15113930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5507-5512.2004
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