Immunogenicity of Constrained Monoclonal Antibody A32-Human Immunodeficiency Virus (HIV) Env gp120 Complexes Compared to That of Recombinant HIV Type 1 gp120 Envelope Glycoproteins

One strategy for the generation of broadly reactive neutralizing antibodies (NA) against human immunodeficiency virus type 1 (HIV-1) primary isolates is to use immunogens that have constrained HIV-1 envelope gp120 conformations reflective of triggered envelope on the surface of virions. A major chan...

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Autors principals: Liao, Hua-Xin, Alam, S. Munir, Mascola, John R., Robinson, James, Ma, Benjiang, Montefiori, David C., Rhein, Maria, Sutherland, Laura L., Scearce, Richard, Haynes, Barton F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC400342/
https://ncbi.nlm.nih.gov/pubmed/15113908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.10.5270-5278.2004
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