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Structural basis for the Nanos-mediated recruitment of the CCR4–NOT complex and translational repression

The RNA-binding proteins of the Nanos family play an essential role in germ cell development and survival in a wide range of metazoan species. They function by suppressing the expression of target mRNAs through the recruitment of effector complexes, which include the CCR4–NOT deadenylase complex. He...

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Bibliographische Detailangaben
Hauptverfasser: Bhandari, Dipankar, Raisch, Tobias, Weichenrieder, Oliver, Jonas, Stefanie, Izaurralde, Elisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003280/
https://ncbi.nlm.nih.gov/pubmed/24736845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.237289.113
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