A novel Netrin-1–sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching

Developmental axon branching dramatically increases synaptic capacity and neuronal surface area. Netrin-1 promotes branching and synaptogenesis, but the mechanism by which Netrin-1 stimulates plasma membrane expansion is unknown. We demonstrate that SNARE-mediated exocytosis is a prerequisite for ax...

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Bibliographic Details
Main Authors: Winkle, Cortney C., McClain, Leslie M., Valtschanoff, Juli G., Park, Charles S., Maglione, Christopher, Gupton, Stephanie L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003241/
https://ncbi.nlm.nih.gov/pubmed/24778312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311003
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