Tissue-specific alterations in expression and function of P-glycoprotein in streptozotocin-induced diabetic rats

AIM: To investigate the changes of expression and function of P-glycoprotein (P-GP) in cerebral cortex, hippocampus, liver, intestinal mucosa and kidney of streptozocin-induced diabetic rats. METHODS: Diabetic rats were prepared via a single dose of streptozocin (65 mg/kg, ip). Abcb1/P-GP mRNA and p...

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Autori principali: Zhang, Lu-lu, Lu, Liang, Jin, Shi, Jing, Xin-yue, Yao, Dan, Hu, Nan, Liu, Li, Duan, Ru, Liu, Xiao-dong, Wang, Guang-ji, Xie, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003124/
https://ncbi.nlm.nih.gov/pubmed/21685928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.33
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