Down-Regulation of TLR9 Expression Affects the Maturation and Function of Murine Bone Marrow-Derived Dendritic Cells Induced by CpG

Toll-like receptor 9 (TLR9) is expressed intracellularly by dendritic cells (DCs) and specifically recognizes unmethylated CpG motif. Recognition of TLR9 to CpG DNA can induce DC maturation followed by the subsequent immune responses. Here, RNA interference (RNAi) was used to identify the effect of...

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Hauptverfasser: Ma, Ling, Zhao, Guangfeng, Hua, Chunyan, Li, Xiaoxi, Zhao, Xiaoyin, Sun, Lingyun, Hou, Yayi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003063/
https://ncbi.nlm.nih.gov/pubmed/19567203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2009.27
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