Down-Regulation of TLR9 Expression Affects the Maturation and Function of Murine Bone Marrow-Derived Dendritic Cells Induced by CpG

Toll-like receptor 9 (TLR9) is expressed intracellularly by dendritic cells (DCs) and specifically recognizes unmethylated CpG motif. Recognition of TLR9 to CpG DNA can induce DC maturation followed by the subsequent immune responses. Here, RNA interference (RNAi) was used to identify the effect of...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ma, Ling, Zhao, Guangfeng, Hua, Chunyan, Li, Xiaoxi, Zhao, Xiaoyin, Sun, Lingyun, Hou, Yayi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003063/
https://ncbi.nlm.nih.gov/pubmed/19567203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2009.27
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